Browsing Doctoral Theses by Thesis Supervisor "Brasch, Nicola"
Now showing items 1-2 of 2
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Mechanistic Studies on the Decomposition of Photoactive Nitrosyl Hydride (HNO) Precursors
(Auckland University of Technology, 2019)Nitroxyl hydride (HNO) is a biologically relevant, highly reactive molecule and is a redox cousin of NO. HNO shows extremely promising pharmacological properties, including treating congestive heart failure. The overarching ... -
Mechanistic Studies on the Photodecomposition of Caged N-hydroxysulfonamides Incorporating the 2-Nitrobenzyl, (2-Nitrophenyl)ethyl and (6-Bromo-7-Hydroxycoumarin-4-Yl)methyl Chromophores
(Auckland University of Technology, 2021)There is accumulating evidence that the redox cousin of nitric oxide (NO), nitroxyl (HNO), is a biologically important signaling molecule. HNO reacts rapidly with thiols and metal centres of metalloproteins. HNO prodrugs ...